CD18 Polyclonal Antibody

Target Information

Target Name	CD18
Uniprot ID	P05107
Cellular Localization	Membrane.
Immunogen	Synthetic peptide corresponding to a sequence at the C terminal of Human CD18, identical to the related Mouse sequences, different from the related Rat sequences.
Function	Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.

Product Details

Description	Rabbit polyclonal antibody to CD18.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide corresponding to a sequence at the C terminal of Human CD18, identical to the related Mouse sequences, different from the related Rat sequences.
Positive Control	WB: Jurkat, CEM, HT1080, SMMc and HeLa whole cell lysate. IHC-P: Human Mammary Cancer Tissue
Application	IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	Preservatives: 0.025% Sodium Azide, 0.025% Thimerosal (Merthiolate) Constituent: 2.5% BSA, 0.45% Sodium Chloride, 0.1% Dibasic Monohydrogen Sodium Phosphate
Handling	Avoid freeze-thaw cycles.