Cat. No.: IBDA-432981
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Online InquiryTarget Information
| Target Name | CD32B |
| Uniprot ID | P31994 |
| Cellular Localization | Cell membrane. |
| Immunogen | Fusion protein. |
| Function | Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. |
Product Details
| Description | Mouse monoclonal antibody to CD32B. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Reactivity | Mouse |
| Immunogen | Fusion protein. |
| Positive Control | IHC-Fr: Mouse spleen fresh tissue. ICC: Mouse splenocytes cells. Flow Cyt: Mouse peripheral blood mononuclear cell. |
| Application | Dot, Flo, ICC, IHC-Fr |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |