CD32B Monoclonal Antibody

Target Information

Target Name	CD32B
Uniprot ID	P31994
Cellular Localization	Cell membrane.
Immunogen	Synthetic peptide corresponding to Human CD32B aa 250-350 (C terminal).
Function	Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Product Details

Description	Rabbit monoclonal antibody to CD32B.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide corresponding to Human CD32B aa 250-350 (C terminal).
Positive Control	Daudi cell lysate, human lymph node tissue.
Application	IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.