Cat. No.: IBDA-432985
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Online InquiryTarget Information
| Target Name | CD32B (phospho Y292) |
| Uniprot ID | P31994 |
| Cellular Localization | Cell membrane. |
| Immunogen | Synthetic peptide. |
| Function | Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. |
Product Details
| Description | Rabbit monoclonal antibody to CD32B (phospho Y292). |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Positive Control | IP: Raji whole cell lysate WB: Daudi (Human Burkitt's lymphoma lymphoblast) treated with 10mM pervanadate for 30 minutes whole cell lysate |
| Application | IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.05% Sodium Azide Constituent: 0.1% BSA, 40% Glycerol, 9.85% Tris Glycine, 50% Tissue Culture Supernatant |
| Handling | Avoid freeze-thaw cycles. |