CD32B (phospho Y292) Polyclonal Antibody

Target Information

Target Name	CD32B (phospho Y292)
Uniprot ID	P31994
Cellular Localization	Cell membrane.
Immunogen	Synthetic peptide within Human CD32B aa 250 to the C-terminus (phospho Y292) conjugated to keyhole limpet haemocyanin.
Function	Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Product Details

Description	Rabbit polyclonal antibody to CD32B (phospho Y292).
Host Species	Rabbit
Clonality	Polyclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Rat, Human
Immunogen	Synthetic peptide within Human CD32B aa 250 to the C-terminus (phospho Y292) conjugated to keyhole limpet haemocyanin.
Positive Control	293T cells. Rat liver tissue. Human colon carcinoma tissue
Application	IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.09% Sodium Azide Constituent: 1% BSA, 50% Glycerol
Handling	Avoid freeze-thaw cycles.