CD32B Polyclonal Antibody

Target Information

Target Name	CD32B
Uniprot ID	P31994
Cellular Localization	Cell membrane.
Immunogen	Synthetic peptide: PDALEEPDDQNRI by a Cysteine residue linker, corresponding to C terminal amino acids 298-310 of Human CD32 (FCGR2B).
Function	Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Product Details

Description	Goat polyclonal antibody to CD32B.
Host Species	Goat
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide: PDALEEPDDQNRI by a Cysteine residue linker, corresponding to C terminal amino acids 298-310 of Human CD32 (FCGR2B).
Positive Control	WB: Daudi cell lysate.
Application	WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at -20 °C
Storage Buffer	pH: 7.30 Preservative: 0.02% Sodium Azide Constituent: 0.5% BSA, Tris Buffered Saline
Handling	Avoid freeze-thaw cycles.