Cat. No.: IBDA-433475
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Online InquiryTarget Information
Target Name | CD33 |
Uniprot ID | P20138 |
Cellular Localization | Cell membrane. |
Immunogen | This product was produced with the following immunogens:Recombinant fragment. |
Function | Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). |
Product Details
Description | Rabbit monoclonal antibody to CD33 - BSA and Azide Free. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Mouse |
Immunogen | This product was produced with the following immunogens:Recombinant fragment. |
Positive Control | Flow Cyt: Mouse blood cell. |
Application | Flo |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | pH: 7.2 Constituent: 100% PBS |