Cat. No.: IBDA-434537
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Online InquiryTarget Information
Target Name | CD41 |
Uniprot ID | P08514 |
Cellular Localization | Membrane. |
Immunogen | Tissue, cells or virus corresponding to Human CD41. |
Function | Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. |
Product Details
Description | Mouse monoclonal antibody to CD41 - BSA and Azide Free. |
Host Species | Mouse |
Clonality | Monoclonal |
Purity | Protein G purified |
Isotype | IgG2a |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Tissue, cells or virus corresponding to Human CD41. |
Positive Control | Flow Cyt: HEL92.1.7 cells. |
Application | Flo, IP |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | Constituent: PBS |
Handling | Do not freeze. |