Cat. No.: IBDA-434537
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Online InquiryTarget Information
| Target Name | CD41 |
| Uniprot ID | P08514 |
| Cellular Localization | Membrane. |
| Immunogen | Tissue, cells or virus corresponding to Human CD41. |
| Function | Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. |
Product Details
| Description | Mouse monoclonal antibody to CD41 - BSA and Azide Free. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein G purified |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Tissue, cells or virus corresponding to Human CD41. |
| Positive Control | Flow Cyt: HEL92.1.7 cells. |
| Application | Flo, IP |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | Constituent: PBS |
| Handling | Do not freeze. |