Cat. No.: IBDA-434528
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Online InquiryTarget Information
Target Name | CD41 |
Uniprot ID | P08514 |
Cellular Localization | Membrane. |
Immunogen | Tissue, cells or virus corresponding to Mouse CD41. |
Function | Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. |
Product Details
Description | PE Rat monoclonal antibody to CD41. |
Host Species | Rat |
Clonality | Monoclonal |
Purity | Protein G purified |
Isotype | IgG1 |
Conjugation | PE/Cy7® |
Reactivity | Mouse |
Immunogen | Tissue, cells or virus corresponding to Mouse CD41. |
Positive Control | Mouse platelets |
Application | Flo |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | pH: 7.20 Preservative: 0.09% Sodium Azide Constituent: 0.1% Gelatin, PBS |