Cat. No.: IBDA-434520
Size:
Online InquiryTarget Information
| Target Name | CD41 |
| Uniprot ID | P08514 |
| Cellular Localization | Membrane. |
| Immunogen | Synthetic peptide. |
| Function | Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. |
Product Details
| Description | Rabbit monoclonal antibody to CD41. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Alexa Fluor® 647 |
| Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Positive Control | IHC-P: Human spleen and bone marrow. |
| Application | IHC-P |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C. Store in the dark |
| Storage Buffer | pH: 7.2 Preservative: 0.02% Sodium Azide Constituent: 30% Glycerol, 1% BSA, 68% PBS |
| Handling | Avoid freeze-thaw cycles. |