CD41 Monoclonal Antibody

Target Information

Target Name	CD41
Uniprot ID	P08514
Cellular Localization	Membrane.
Immunogen	Synthetic peptide.
Function	Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Product Details

Description	Rabbit monoclonal antibody to CD41 - Low Endotoxin, Azide Free.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Human
Immunogen	Synthetic peptide.
Positive Control	Human platelet, fetal liver and placenta lysates. Human spleen tissue
Application	ICC/IF, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	pH: 7.2 Constituent: PBS
Handling	Do not freeze.