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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

CD41 Monoclonal Antibody

Cat. No.: IBDA-434527

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Target Information

Target Name CD41
Uniprot ID P08514
Cellular Localization Membrane.
Immunogen Tissue, cells or virus corresponding to Mouse CD41.
Function Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Product Details

Description PE Rat monoclonal antibody to CD41.
Host Species Rat
Clonality Monoclonal
Purity Size exclusion
Isotype IgG1
Conjugation PE
Reactivity Mouse
Immunogen Tissue, cells or virus corresponding to Mouse CD41.
Positive Control Flow Cytometry: Murine thrombocytes.
Application Flo

Storage & Handling

Shipping Shipped at 4 °C.
Storage Store at 4 °C. Store in the dark
Storage Buffer pH: 7.40
Preservative: 0.0975% Sodium Azide
Constituent: PBS
! For research use only, not intended for any clinical use.