CD43 Monoclonal Antibody

Target Information

Target Name	CD43
Uniprot ID	P16150
Cellular Localization	Membrane.
Immunogen	Recombinant fragment.
Function	One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.

Product Details

Description	Rabbit monoclonal antibody to CD43.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant fragment.
Positive Control	WB: HL-60, Ramos, IM-9 and THP-1 whole cell lysates. IHC-P: Human tonsil and B-cell lymphoma tissues. ICC/IF: IM-9 cells. Flow: IM-9 cells.
Application	Flo, ICC/IF, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: PBS, 50% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.