CD43 Monoclonal Antibody

Target Information

Target Name	CD43
Uniprot ID	P16150
Cellular Localization	Membrane.
Immunogen	Synthetic peptide within Human CD43 aa 200-300 (internal sequence).
Function	One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.

Product Details

Description	Rabbit monoclonal antibody to CD43.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A/G purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide within Human CD43 aa 200-300 (internal sequence).
Positive Control	IHC-P: Human tonsil and spleen tissue WB: Jurkat cells. Flow: Jurkat cells, IM-9 cells ICC/IF: IM-9 cells
Application	Flo, ICC/IF, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	pH: 7.60 Preservative: 0.1% Sodium Azide Constituent: PBS, 1% BSA