CD43 Monoclonal Antibody

Target Information

Target Name	CD43
Uniprot ID	P16150
Cellular Localization	Membrane.
Immunogen	Full length native protein (purified) corresponding to Human CD43 aa 1 to the C-terminus.
Function	One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.

Product Details

Description	Mouse monoclonal antibody to CD43.
Host Species	Mouse
Clonality	Monoclonal
Purity	Immunogen affinity purified
Isotype	IgG1
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Full length native protein (purified) corresponding to Human CD43 aa 1 to the C-terminus.
Positive Control	Human peripheral blood lymphocytes.
Application	Flo

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.09% Sodium Azide containing Protein Stabilizer
Handling	Avoid freeze-thaw cycles.