Cat. No.: IBDA-433744
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Online InquiryTarget Information
| Target Name | CD43 |
| Uniprot ID | P16150 |
| Cellular Localization | Membrane. |
| Immunogen | Full length native protein (purified) corresponding to Human CD43 aa 1 to the C-terminus. |
| Function | One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response. |
Product Details
| Description | Mouse monoclonal antibody to CD43. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Full length native protein (purified) corresponding to Human CD43 aa 1 to the C-terminus. |
| Positive Control | Human peripheral blood lymphocytes. |
| Application | Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.09% Sodium Azide containing Protein Stabilizer |
| Handling | Avoid freeze-thaw cycles. |