CD43 Monoclonal Antibody

Target Information

Target Name	CD43
Uniprot ID	P16150
Cellular Localization	Membrane.
Immunogen	Tissue, cells or virus corresponding to Rat CD43.
Function	One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.

Product Details

Description	Mouse monoclonal antibody to CD43.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein G purified
Isotype	IgG1
Conjugation	Alexa Fluor® 488
Reactivity	Rat
Immunogen	Tissue, cells or virus corresponding to Rat CD43.
Positive Control	Flow Cyt: Lewis rat splenocytes.
Application	Flo

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C. Store in the dark
Storage Buffer	Preservative: 0.02% Sodium Azide Constituent: 30% Glycerol, 1% BSA, PBS
Handling	Avoid freeze-thaw cycles.