Cat. No.: IBDA-433738
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Online InquiryTarget Information
Target Name | CD43 |
Uniprot ID | P16150 |
Cellular Localization | Membrane. |
Immunogen | Tissue, cells or virus corresponding to Human CD43. |
Function | One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response. |
Product Details
Description | Biotin Mouse monoclonal antibody to CD43. |
Host Species | Mouse |
Clonality | Monoclonal |
Purity | Size exclusion |
Isotype | IgG1 |
Conjugation | Biotin |
Reactivity | Human |
Immunogen | Tissue, cells or virus corresponding to Human CD43. |
Application | Flo, IHC-P, IP, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C |
Storage Buffer | pH: 8.0 Preservative: 0.097% Sodium Azide |
Handling | Avoid freeze-thaw cycles. |