CD44 Monoclonal Antibody

Target Information

Target Name	CD44
Uniprot ID	P16070
Cellular Localization	Membrane.
Immunogen	Recombinant fragment.
Function	Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

Product Details

Description	Rabbit monoclonal antibody to CD44.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Rat, Human
Immunogen	Recombinant fragment.
Positive Control	WB: Human fetal brain, fetal heart, fetal kidney and fetal spleen lysates. Human thymus and skin lysates. HAP1, HeLa, A549, U-87 MG, C6, RAW 264.7, PC-12 and NIH/3T3 whole cell lysates. Mouse brain and spleen lysates. Rat brain, heart, kidney and spleen lysates. IHC-P: Human breast, kidney, tonsil and breast cancer tissues. Mouse colon, stomach and spleen tissues. Rat stomach and spleen tissues. IP: A549 whole cell lysate.
Application	IHC-P, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: PBS, 40% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.