CD44 Monoclonal Antibody

Target Information

Target Name	CD44
Uniprot ID	P16070
Cellular Localization	Membrane.
Immunogen	Synthetic peptide within Human CD44 aa 700 to the C-terminus (C terminal).
Function	Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

Product Details

Description	Rabbit monoclonal antibody to CD44.
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Human
Immunogen	Synthetic peptide within Human CD44 aa 700 to the C-terminus (C terminal).
Positive Control	WB: 786-O, KG-1, HeLa and A549 cell lysates. EL4 and BW5147.3 cell lysates. IHC-P: Human head and neck squamous cell carcinoma tissue. ICC: HCT116 cells. Flow Cyt: HeLa cells.
Application	Flo, ICC, IHC-P, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.8 Preservative: 0.09% Sodium Azide Constituent: 98% Borate Buffered Saline, 0.1% BSA
Handling	Avoid freeze-thaw cycles.