Cat. No.: IBDA-433835
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Online InquiryTarget Information
Target Name | CD44 |
Uniprot ID | P16070 |
Cellular Localization | Membrane. |
Immunogen | Tissue, cells or virus. |
Function | Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. |
Product Details
Description | Mouse monoclonal antibody to CD44. |
Host Species | Mouse |
Clonality | Monoclonal |
Purity | Protein G purified |
Isotype | IgG2a |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Tissue, cells or virus. |
Positive Control | In Flow Cytometry, this antibody gave a positive signal in peripheral blood lymphocytes. In IHC, this antibody gave a positive signal in human kidney carcinoma sections. ICC/IF: A431 cell line. |
Application | Flo, ICC/IF, IHC-P |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C |
Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: PBS, 6.97% L-Arginine |
Handling | Avoid freeze-thaw cycles. |