CD44 Monoclonal Antibody

Target Information

Target Name	CD44
Uniprot ID	P16070
Cellular Localization	Membrane.
Immunogen	Recombinant fragment corresponding to Human CD44 (extracellular).
Function	Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

Product Details

Description	Mouse monoclonal antibody to CD44 - Extracellular domain.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein G purified
Isotype	IgG2a
Conjugation	Unconjugated
Reactivity	Human, Recombinant fragment
Immunogen	Recombinant fragment corresponding to Human CD44 (extracellular).
Positive Control	ICC/IF: MeWo cells. WB: A549, MDA-MB-231, MeWo cell lysate. Human breast, lung, skin and brain tissue lysate.
Application	ELISA, ICC/IF, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	Preservative: 0.05% Sodium Azide Constituent: PBS, 50% Glycerol, 0.1% BSA
Handling	Avoid freeze-thaw cycles.