Cat. No.: IBDA-433812
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Online InquiryTarget Information
| Target Name | CD44 |
| Uniprot ID | P16070 |
| Cellular Localization | Membrane. |
| Immunogen | Synthetic peptide within Human CD44 aa 650-750. |
| Function | Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. |
Product Details
| Description | Rabbit polyclonal antibody to CD44. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Rat, Human |
| Immunogen | Synthetic peptide within Human CD44 aa 650-750. |
| Positive Control | IHC-P: Human squamous cell carcinoma, lung cancer, skin, cervical cancer. Mouse spleen and plasmacytoma tissue. rat spleen tissue. WB: A549, HeLa, U2OS, TCMK-1, NIH/3T3 cells IP: HeLa and HAP1 cells. |
| Application | IHC-P, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7 Preservative: 0.09% Sodium Azide Constituent: 99% Tris Citrate/Phosphate |