Cat. No.: IBDA-434431
Size:
Online InquiryTarget Information
Target Name | CD45 |
Uniprot ID | P08575 |
Cellular Localization | Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts. |
Immunogen | Synthetic peptide. |
Function | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. |
Product Details
Description | Rabbit monoclonal antibody to CD45 - BSA and Azide Free. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Synthetic peptide. |
Positive Control | WB: Jurkat and THP-1 cell lysates. Flow Cyt: 293T and Jurkat cells. ICC/IF: Jurkat and Daudi cells. IHC-P: Kidney, colon lymphoid, skeletal muscle, spleen, and Human tonsil tissues. |
Application | Flo, ICC/IF, IHC-P, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | pH: 7.2 Constituent: PBS |
Handling | Do not freeze. |