Products
Inquiry

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

CD45 Monoclonal Antibody

Cat. No.: IBDA-434435

Size:

Target Information

Target Name CD45
Uniprot ID P08575
Cellular Localization Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts.
Immunogen Synthetic peptide.
Function Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.

Product Details

Description Rabbit monoclonal antibody to CD45.
Host Species Rabbit
Clonality Monoclonal
Purity Protein A purified
Isotype IgG
Conjugation Unconjugated
Reactivity Mouse, Human
Immunogen Synthetic peptide.
Positive Control WB: J774A.1, WEHI-231 and Jurkat whole cell lysates. mouse thymus and spleen lysates, THP-1, MCF7.
IP: J774A.1 whole cell lysate.
IHC-P: Human tonsil tissue and Mouse spleen tissue.
Application IHC-P, IP, WB

Storage & Handling

Shipping Shipped at 4 °C.
Storage Short term: 4 °C. Long term: -20 °C
Storage Buffer pH: 7.2
Preservative: 0.01% Sodium Azide
Constituent: PBS, 40% Glycerol, 0.05% BSA
Handling Avoid freeze-thaw cycles.
! For research use only, not intended for any clinical use.