CD45 Monoclonal Antibody

Target Information

Target Name	CD45
Uniprot ID	P08575
Cellular Localization	Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts.
Immunogen	Synthetic peptide.
Function	Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.

Product Details

Description	Rabbit monoclonal antibody to CD45.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Alexa Fluor® 488
Reactivity	Human
Immunogen	Synthetic peptide.
Positive Control	Flow Cyt: Jurkat cells. ICC/IF: Daudi cells
Application	Flo, ICC/IF

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C. Store in the dark
Storage Buffer	pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 30% Glycerol, 1% BSA, PBS
Handling	Avoid freeze-thaw cycles.