Cat. No.: IBDA-434385
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Online InquiryTarget Information
Target Name | CD45 |
Uniprot ID | P08575 |
Cellular Localization | Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts. |
Immunogen | The details of the immunogen for this antibody are not available. |
Function | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. |
Product Details
Description | Biotin Rat monoclonal antibody to CD45. |
Host Species | Rat |
Clonality | Monoclonal |
Purity | Affinity purified |
Isotype | IgG2b |
Conjugation | Biotin |
Reactivity | Mouse |
Immunogen | The details of the immunogen for this antibody are not available. |
Positive Control | Flow Cyt: C57Bl/6 splenocytes |
Application | Flo |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C. Store in the dark |
Storage Buffer | pH: 7.20 Preservative: 0.09% Sodium Azide Constituent: 0.12% Monobasic Dihydrogen Sodium Phosphate, 0.87% Sodium Chloride |
Handling | Avoid freeze-thaw cycles. |