CD45 Monoclonal Antibody

Target Information

Target Name	CD45
Uniprot ID	P08575
Cellular Localization	Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts.
Immunogen	Synthetic peptide.
Function	Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.

Product Details

Description	APC Rabbit monoclonal antibody to CD45.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	APC
Reactivity	Human
Immunogen	Synthetic peptide.
Positive Control	Flow Cyt (Intra): Jurkat cells
Application	Flo

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at 4 °C. Store in the dark
Storage Buffer	pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: PBS, 1% BSA
Handling	Do not freeze.