Cat. No.: IBDA-434410
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Online InquiryTarget Information
Target Name | CD45 |
Uniprot ID | P08575 |
Cellular Localization | Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts. |
Immunogen | Synthetic peptide. |
Function | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. |
Product Details
Description | PerCP Rabbit monoclonal antibody to CD45. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | PerCP |
Reactivity | Human |
Immunogen | Synthetic peptide. |
Positive Control | Flow Cyt (Intra): Jurkat cells |
Application | Flo |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Upon delivery aliquot. Store at 4 °C. Store in the dark |
Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 1% BSA, PBS |
Handling | Do not freeze. |