CD45 Monoclonal Antibody

Target Information

Target Name	CD45
Uniprot ID	P08575
Cellular Localization	Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts.
Immunogen	Synthetic peptide within Human CD45 aa 1250-1306 (C terminal).
Function	Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.

Product Details

Description	Rabbit monoclonal antibody to CD45.
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide within Human CD45 aa 1250-1306 (C terminal).
Application	Flo, ICC, IHC-P, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.8 Preservative: 0.09% Sodium Azide Constituent: 98% Borate Buffered Saline, 0.1% BSA
Handling	Avoid freeze-thaw cycles.