Cat. No.: IBDA-434442
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Online InquiryTarget Information
Target Name | CD45 |
Uniprot ID | P08575 |
Cellular Localization | Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts. |
Immunogen | This product was produced with the following immunogens:Synthetic peptide. |
Function | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. |
Product Details
Description | Rabbit recombinant multiclonal antibody to CD45 - BSA and Azide Free. |
Host Species | Rabbit |
Clonality | Recombinant Multiclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Mouse, Rat, Human |
Immunogen | This product was produced with the following immunogens:Synthetic peptide. |
Positive Control | WB: Jurkat, Mouse thymus, Rat thymus lysates. IHC-P: Human tonsil, spleen, colon cancer, Mouse spleen and Rat spleen tissues. ICC: Jurkat cells. Flow Cyt (Intra): Human PBMCs, Jurkat cells, Mouse PBMCs. IP: Jurkat cell. |
Application | Flo, ICC, IHC-P, IP, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | pH: 7.20 Constituent: 100% PBS |