Cat. No.: IBDA-434453
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Online InquiryTarget Information
Target Name | CD45RA |
Uniprot ID | P08575 |
Cellular Localization | Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts. |
Immunogen | Full length native protein (purified) corresponding to Rat CD45RA. |
Function | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. |
Product Details
Description | Mouse monoclonal antibody to CD45RA - BSA and Azide Free. |
Host Species | Mouse |
Clonality | Monoclonal |
Purity | Protein G purified |
Isotype | IgG1 |
Conjugation | Unconjugated |
Reactivity | Rat, Human |
Immunogen | Full length native protein (purified) corresponding to Rat CD45RA. |
Positive Control | Flow Cyt: Lewis rat splenocytes. IHC-Fr: Rat Spleen |
Application | Flo, IHC-Fr |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | Constituent: PBS |
Handling | Do not freeze. |