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CD45RA Monoclonal Antibody - BSA and Azide Free

Cat. No.: IBDA-434453

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Target Information

Target Name CD45RA
Uniprot ID P08575
Cellular Localization Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts.
Immunogen Full length native protein (purified) corresponding to Rat CD45RA.
Function Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.

Product Details

Description Mouse monoclonal antibody to CD45RA - BSA and Azide Free.
Host Species Mouse
Clonality Monoclonal
Purity Protein G purified
Isotype IgG1
Conjugation Unconjugated
Reactivity Rat, Human
Immunogen Full length native protein (purified) corresponding to Rat CD45RA.
Positive Control Flow Cyt: Lewis rat splenocytes.
IHC-Fr: Rat Spleen
Application Flo, IHC-Fr

Storage & Handling

Shipping Shipped at 4 °C.
Storage Store at 4 °C
Storage Buffer Constituent: PBS
Handling Do not freeze.
! For research use only, not intended for any clinical use.