Cat. No.: IBDA-432064
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Online InquiryTarget Information
| Target Name | CD47 |
| Uniprot ID | Q08722 |
| Cellular Localization | Cell membrane. |
| Immunogen | Synthetic peptide within Human CD47 aa 50-150 (internal sequence). |
| Function | Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. |
Product Details
| Description | Rabbit monoclonal antibody to CD47 - BSA and Azide Free. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A/G purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide within Human CD47 aa 50-150 (internal sequence). |
| Positive Control | IHC-P: Human prostate adenocarcinoma tissue. |
| Application | IHC-P |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.20 Constituent: PBS |
| Handling | Do not freeze. |