Cat. No.: IBDA-432061
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Online InquiryTarget Information
| Target Name | CD47 |
| Uniprot ID | Q08722 |
| Cellular Localization | Cell membrane. |
| Immunogen | Recombinant full length protein corresponding to Human CD47. |
| Function | Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. |
Product Details
| Description | Mouse monoclonal antibody to CD47 - BSA and Azide Free. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein A/G purified |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant full length protein corresponding to Human CD47. |
| Positive Control | Flow Cyt: Live Jurkat cells. ICC: MCF-7 and live Jurkat cells. |
| Application | Flo, ICC |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Constituent: 100% PBS |
| Handling | Avoid freeze-thaw cycles. |