Cat. No.: IBDA-432059
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Online InquiryTarget Information
Target Name | CD47 |
Uniprot ID | Q08722 |
Cellular Localization | Cell membrane. |
Immunogen | Recombinant fragment. |
Function | Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. |
Product Details
Description | Rabbit monoclonal antibody to CD47. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Recombinant fragment. |
Positive Control | WB: Jurkat, U937, NIH:OVCAR-3, Wild-type HEK-293T, CD47 CRISPR-Cas9 edited HEK-293T, whole cell lysates. IHC-P: Human tonsil, human ovarian cancer, human gastric cancer FFPE tissue sections. human wild-type HEK-293T cell pellet, human CD47 CRISPR-Cas9 edited HEK-293T cell pellet. |
Application | IHC-P, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C |
Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA |
Handling | Avoid freeze-thaw cycles. |