CD47 Monoclonal Antibody

Target Information

Target Name	CD47
Uniprot ID	Q08722
Cellular Localization	Cell membrane.
Immunogen	Synthetic peptide.
Function	Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

Product Details

Description	Rabbit monoclonal antibody to CD47.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide.
Positive Control	WB: HEK-293T, Jurkat, U937, A549 and U-2 OS whole cell lysates. IHC-P: Human ovary carcinoma, liver and placenta tissues.
Application	IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: PBS, 40% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.