CD47 Monoclonal Antibody

Target Information

Target Name	CD47
Uniprot ID	Q08722
Cellular Localization	Cell membrane.
Immunogen	Tissue, cells or virus corresponding to Rat CD47.
Function	Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

Product Details

Description	Mouse monoclonal antibody to CD47.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein G purified
Isotype	IgG1
Conjugation	Unconjugated
Reactivity	Rat
Immunogen	Tissue, cells or virus corresponding to Rat CD47.
Positive Control	Flow Cyt: Lewis rat splenocytes. IHC-Fr: Rat Placenta
Application	Flo, IHC-Fr

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	Preservative: 0.02% Sodium Azide Constituent: PBS
Handling	Avoid freeze-thaw cycles.