CD47 Polyclonal Antibody

Target Information

Target Name	CD47
Uniprot ID	Q08722
Cellular Localization	Cell membrane.
Immunogen	Synthetic peptide corresponding to Human CD47 aa 250 to the C-terminus.
Function	Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

Product Details

Description	Goat polyclonal antibody to CD47.
Host Species	Goat
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide corresponding to Human CD47 aa 250 to the C-terminus.
Positive Control	Human hippocampus, HeLa and Jurkat lysates.
Application	WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.30 Preservative: 0.02% Sodium Azide Constituent: 99% Tris Buffered Saline, 0.5% BSA
Handling	Avoid freeze-thaw cycles.