Cat. No.: IBDA-432049
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Online InquiryTarget Information
| Target Name | CD47 |
| Uniprot ID | Q08722 |
| Cellular Localization | Cell membrane. |
| Immunogen | This product was produced with the following immunogens:Synthetic peptide. |
| Function | Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. |
Product Details
| Description | Rabbit recombinant multiclonal antibody to CD47 - BSA and Azide Free. |
| Host Species | Rabbit |
| Clonality | Recombinant Multiclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | This product was produced with the following immunogens:Synthetic peptide. |
| Positive Control | WB: Jurkat, HEK-293T and U-937 whole cell lysates. human ovary cancer tissue lysate. IHC-P: Human spleen, placenta, breast cancer and ovarian carcinoma tissue. ICC/IF: Jurkat cells. Flow Cyt: U-937 and Jurkat cells. |
| Application | Flo, ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.2 Constituent: 100% PBS |