Cat. No.: IBDA-434612
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Online InquiryTarget Information
Target Name | CD55 |
Uniprot ID | P08174 |
Cellular Localization | Cell membrane. |
Immunogen | Recombinant fragment corresponding to Human CD55. |
Function | This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. |
Product Details
Description | Mouse monoclonal antibody to CD55 - Extracellular domain. |
Host Species | Mouse |
Clonality | Monoclonal |
Purity | Protein G purified |
Isotype | IgG2a |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Recombinant fragment corresponding to Human CD55. |
Positive Control | WB: A549, MDA-MB-231 and A431 cell lysates. human lung tissue lysate (Native). ICC/IF: MDA-MB-231 cells. |
Application | ICC/IF, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C |
Storage Buffer | Preservative: 0.05% Sodium Azide Constituent: PBS, 50% Glycerol, 0.1% BSA |
Handling | Avoid freeze-thaw cycles. |