CD59 Monoclonal Antibody - BSA and Azide Free

Target Information

Target Name	CD59
Uniprot ID	P13987
Cellular Localization	Cell membrane. Secreted. Soluble form found in a number of tissues.
Immunogen	Recombinant full length protein corresponding to Human CD59 aa 1 to the C-terminus.
Function	Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.

Product Details

Description	Mouse monoclonal antibody to CD59 - BSA and Azide Free.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein G purified
Isotype	IgG1
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant full length protein corresponding to Human CD59 aa 1 to the C-terminus.
Positive Control	Human tongue and tonsil tissues.
Application	IHC-P

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Constituent: 100% PBS
Handling	Avoid freeze-thaw cycles.