CD59 Monoclonal Antibody

Target Information

Target Name	CD59
Uniprot ID	P13987
Cellular Localization	Cell membrane. Secreted. Soluble form found in a number of tissues.
Immunogen	Tissue, cells or virus corresponding to Human CD59.
Function	Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.

Product Details

Description	Mouse monoclonal antibody to CD59.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG2a
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Tissue, cells or virus corresponding to Human CD59.
Positive Control	ICC/IF: Human fibrosarcoma cells. Flow Cyt: HT1080 cells. IHC: human placenta tissue
Application	Flo, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.40 Preservative: 0.097% Sodium Azide Constituent: PBS
Handling	Do not freeze.