Cat. No.: IBDA-434000
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Online InquiryTarget Information
| Target Name | CD59 |
| Uniprot ID | P13987 |
| Cellular Localization | Cell membrane. Secreted. Soluble form found in a number of tissues. |
| Immunogen | Tissue, cells or virus corresponding to Human CD59. |
| Function | Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. |
Product Details
| Description | Mouse monoclonal antibody to CD59. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Human |
| Immunogen | Tissue, cells or virus corresponding to Human CD59. |
| Positive Control | Flow Cyt: blood Jeg3 cell line IF/ICC |
| Application | Flo, ICC/IF, IHC-P, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.097% Sodium Azide Constituent: PBS |
| Handling | Avoid freeze-thaw cycles. |