CD68 Monoclonal Antibody

Target Information

Target Name	CD68
Uniprot ID	P34810
Cellular Localization	Cell membrane and Endosome membrane. Lysosome membrane.
Immunogen	Synthetic peptide.
Function	Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Product Details

Description	Rabbit monoclonal antibody to CD68.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide.
Positive Control	WB: Human tonsil, fetal liver and fetal spleen lysates. THP-1 and U937 whole cell lysates. IHC-P: Human tonsil and cervix carcinoma. mIHC: Human liver tissue, human duodenum tissue, human colon tissue. ICC/IF: THP-1 and U937 cells.
Application	ICC/IF, IHC-P, mIHC, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: PBS, 40% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.