CD68 Polyclonal Antibody

Target Information

Target Name	CD68
Uniprot ID	P34810
Cellular Localization	Cell membrane and Endosome membrane. Lysosome membrane.
Immunogen	Synthetic peptide corresponding to Mouse CD68 aa 312-326 (internal sequence).
Function	Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Product Details

Description	Rabbit polyclonal antibody to CD68.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Rat
Immunogen	Synthetic peptide corresponding to Mouse CD68 aa 312-326 (internal sequence).
Positive Control	IHC-P: Rat and mouse liver tissue, Mouse spleen, skin, and brain tissues. IHC-Fr: Rat liver tissue. WB: Wild-type RAW 264.7, Neuro-2a cell lysates, Rat and Mouse spleen tissue lysates. Raw264.7 cell lysate.
Application	IHC-Fr, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at -20 °C
Storage Buffer	Constituent: 0.45% Sodium Chloride, 0.1% Dibasic Monohydrogen Sodium Phosphate, 5.61% Trehalose
Handling	Avoid freeze-thaw cycles.