Cat. No.: IBDA-432719
Size:
Online InquiryTarget Information
| Target Name | CD86 |
| Uniprot ID | P42081 |
| Cellular Localization | Membrane. |
| Immunogen | Recombinant full length protein corresponding to Human CD86. |
| Function | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. |
Product Details
| Description | Mouse monoclonal antibody to CD86 - BSA and Azide Free. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein A/G purified |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant full length protein corresponding to Human CD86. |
| Positive Control | WB: Raji and Daudi cell lysate. Human liver lysate. ICC: Raji cells. IHC-P: Human melanoma tissue. |
| Application | ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Constituent: PBS |
| Handling | Avoid freeze-thaw cycles. |