CD86 Monoclonal Antibody

Target Information

Target Name	CD86
Uniprot ID	P42081
Cellular Localization	Membrane.
Immunogen	Recombinant fragment corresponding to Human CD86 (extracellular).
Function	Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.

Product Details

Description	Rabbit monoclonal antibody to CD86 - BSA free.
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant fragment corresponding to Human CD86 (extracellular).
Positive Control	WB: HDLM-2 whole cell lysate. IP: HDLM-2 whole cell lysate. ICC: HDLM-2 cells.
Application	ICC, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.8 Preservative: 0.09% Sodium Azide Constituent: 99% Borate Buffered Saline
Handling	Avoid freeze-thaw cycles.