Cat. No.: IBDA-432707
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Online InquiryTarget Information
| Target Name | CD86 |
| Uniprot ID | P42081 |
| Cellular Localization | Membrane. |
| Immunogen | LPS-activated CBA/Cs Mouse splenic B cells. |
| Function | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. |
Product Details
| Description | Rat monoclonal antibody to CD86. |
| Host Species | Rat |
| Clonality | Monoclonal |
| Purity | Affinity purified |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Reactivity | Mouse |
| Immunogen | LPS-activated CBA/Cs Mouse splenic B cells. |
| Positive Control | Mouse splenocytes. |
| Application | BL, Flo, FuncS, ICC/IF, IHC-Fr, IP |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C. Store undiluted |
| Storage Buffer | pH: 7.20 Preservative: 0.09% Sodium Azide Constituent: 0.87% Sodium Chloride, 0.14% Monobasic Dihydrogen Sodium Phosphate |
| Handling | Do not freeze. |