Cat. No.: IBDA-432722
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Online InquiryTarget Information
| Target Name | CD86 |
| Uniprot ID | P42081 |
| Cellular Localization | Membrane. |
| Immunogen | Recombinant full length protein corresponding to Human CD86. |
| Function | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. |
Product Details
| Description | Rabbit monoclonal antibody to CD86. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A/G purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant full length protein corresponding to Human CD86. |
| Positive Control | IHC-P: Human colon tissue. |
| Application | IHC-P |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.05% Sodium Azide Constituent: PBS, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |