Cat. No.: IBDA-432699
Size:
Online InquiryTarget Information
| Target Name | CD86 |
| Uniprot ID | P42081 |
| Cellular Localization | Membrane. |
| Immunogen | Tissue, cells or virus corresponding to Human CD86. |
| Function | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. |
Product Details
| Description | APC Mouse monoclonal antibody to CD86, prediluted. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Size exclusion |
| Isotype | IgG1 |
| Conjugation | APC |
| Reactivity | Human |
| Immunogen | Tissue, cells or virus corresponding to Human CD86. |
| Positive Control | Human whole blood. |
| Application | Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.1% Sodium Azide Constituent: 99% PBS, 0.2% BSA |