Cat. No.: IBDA-432693
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Online InquiryTarget Information
| Target Name | CD86 |
| Uniprot ID | P42081 |
| Cellular Localization | Membrane. |
| Immunogen | Tissue, cells or virus. |
| Function | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. |
Product Details
| Description | Mouse monoclonal antibody to CD86. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Affinity purified |
| Isotype | IgG1 |
| Conjugation | Alexa Fluor® 488 |
| Reactivity | Rat |
| Immunogen | Tissue, cells or virus. |
| Positive Control | Flow Cyt: LPS activated Lewis rat splenocytes. |
| Application | Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C. Store in the dark |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 30% Glycerol, 1% BSA, PBS |
| Handling | Avoid freeze-thaw cycles. |